2013年12月27日星期五

Stem Cell Therapy

Stem cell therapy is a biotherapy. It brings new hope for people with refractory and incurable diseases. In clinic, it has showed enormous curative effects in treating kidney disease.
Stem Cell Therapy has already been used in clinic in some countries to treat chronic kidney failure fundamentally. Stem cells are a group of cells which have the capacity of self-update and differentiation. They can produce amount of daughter cells under proper conditions. We capitalize on the self-update and differentiation capacity of the stem cells to repair damaged inherent cells and recover kidney function. After stem cells are transfused to human body, they will transfer to kidney lesions automatically through the function of automatic homing, generate kinds of desired cells and then repair the connatural renal cell, recover renal function and block up and reverse the progression of renal fibrosis.
Features of stem cell therapy
1. It is widely used to treat diseases and conditions.
2. Free of toxicity and immune rejection.
3. The best carrier of immunization and gene therapy.
4. It can be used before patient understanding pathogenesis completely.
With stem cell therapy,the patients do not need have surgery. So there is no surgical risk in treating disease.As stem cells are primary cells with weak antigenicity on the surface, they will not cause rejection reaction after after being injected into body.
Indications of stem cell therapy
I. Renal injury caused by Autoimmune Diseases and connective tissue disease: Lupus Nephritis, Anaphylactic Purpura Nephritis, Glomerular Basement Membrane Disease, Primary Renal Vasculitis, Chronic Infectious Arthritis, Ankylosing Spondylitis, Psoriasis, Sicca Syndrome, Scleroderma, Polymyositis, Dermatomyositis, Behcet's Disease Etc.
II. Primary kidney disease such as Primary Nephrotic Syndrome, Acute Glomerulonephritis,Chronic Glomerulonephritis,IgA Nephropathy,MPGN,FSGS,and Membrane Proliferative Glomerulonephritis.
III. Renal injury caused by Metabolic Diseases: Diabetic Nephropathy, Hyperuricemic Nephropaihy and hypokalemic nephropathy.
IV. Renal tubular disease and renal interstitial disease: Renal Tubular Acidosis, various kinds of acute and chronic interstitial nephritis;
V. Renal injury caused by infectious diseases: hepatitis B Virus associated glomerulonephritis, hepatitis C Virus associated glomerulonephritis
VI. cardiac function and IV
VII. Cardiorenal Syndrome and Hepatorenal Syndrome
VIII.Renal Injury caused by hypertension.
IX.Hereditary kidney diseases: Alport nephritis, thin glomerular basement membrane disease, Fabry disease etc.;
X. Polycystic Kidney Disease
Contraindications of Stem Cell Therapy
I. Patient who is allergic to stem cell or patient with serious allergy;
II. pregnant women (woman in lactation period is allowed)
III. Infected patients who is still out of control;
IV. Serious mental illness patient, including patient with tristimania;
V. Severe Hypertension (BP is higher than 160/100mmHg)
VI. Patient with III and IV cardiac function, coronary disease, unstable angina, myocardial ischemia
VII. Patients with obvious renal atrophy
VIII. Patients with severe bleeding tendency
IX. Patients who are taking part in clinical research.

X. Polycystic Kidney Disease

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