What Are the Complications of FSGS

FSGS mostly occurs in children and adolescents, men slightly more than women. A few patients before the onset of upper respiratory tract infection or allergic reactions. Initial symptoms of nephrotic syndrome is the most common, about two-thirds of patients with massive proteinuria and severe edema, proteinuria in 1 ~ 30g / d, about 50% of patients with hematuria, microscopic hematuria common , occasionally gross hematuria.

There are many FSGS treatment, but complications arise if FSGS that will increase the difficulty of treatment, the following tell you about all those complications FSGS.

1, thrombosis, embolic complications due to the blood concentration and hyperlipidemia cause an increase in blood viscosity; in addition, due to the loss of certain proteins, decompensated liver protein synthesis increased, causing the body of coagulation and fibrinolysis system imbalance. Therefore, prone to blood clots, embolic complications.

2, acute renal failure, nephrotic syndrome patients may be due to lack of effective blood volume caused the decline in renal blood flow, induce pre-renal azotemia. Because of the high degree of interstitial edema, tubular pressure and a lot of protein renal tubular obstruction and tubular intraluminal pressure, indirectly caused a sharp reduction in glomerular filtration rate, leading to acute renal failure.

3, infection and protein loss, malnutrition, immune dysfunction and glucocorticoid therapy. Infection is a common complication of nephrotic syndrome, due to the application of glucocorticoid, which is not obvious clinical signs of infection, although there are a variety of antibiotics to choose from, but if not treated early or not complete, the infection is still cause illness the main reason for recurrence and poor efficacy or even lead to death of the patient, should be highly valued.

4, protein and fat metabolism long hypoalbuminemia can lead to malnutrition, growth retardation in children; immunoglobulin reduction caused by low immunity, prone to cause infection; metal-binding protein loss can trace elements (iron, copper, zinc etc.) deficiency; endocrine hormone binding protein deficiency can induce endocrine disorders; drug binding protein may reduce the effects of some drugs pharmacokinetics (plasma free drug concentration, excretion acceleration), the impact of drug efficacy. Hyperlipidemia increased blood viscosity, promote thrombotic, embolic complications, cardiovascular complications will increase, and may contribute to glomerular sclerosis and tubular - interstitial diseases occur, to promote chronic kidney disease progress.

The treatment of FSGS still controversial in the past that this disease poor efficacy, treatment is more difficult, and no mature and effective treatment, patients generally 5 to 10 years enters the renal failure stage. In recent years, a large retrospective study showed a positive result in the removal and treatment of the cause of FSGS, and diuretic, blood pressure and other symptomatic treatment, can induce remission of nephrotic syndrome, prevent and delay the progression of the disease.

FSGS really have to say is a more complex disease, because we need to repair the kidney tissue hardening, it is a very difficult thing. We recommend this to everyone Shijiazhuang Kidney Disease Hospital characteristics therapy - Stem cell transplantation therapy, which can clean our blood toxins, produce new cells to replace necrotic tissue, thus effectively solve the problem of hardening cell.

If you are interested in our treatment, the treatment of the issue would like to know more, you can contact our online doctors, or we, our doctors can provide free treatment and dietary advice to contact you by email.