IgA or IgA Nephropathy, is a kind of autoimmune disease with depositions of
IgA
or IgA-focusing immune complexes in the area of glomerular membrane. It is
presented by recurrent Hematuresis, whether it is gross Hematuresis or naked
Hematuresis. So you may ask whether Hematuresis is serious or not.
The biggest character of IgA just shows up as the naked Hematuresis or
microscopic hematuria. Hematuria refers your urine has blood. Besides
Hematuresis, there are also other symptoms such as proteinuria, swelling, high
blood pressure even the Renal Insufficiency.
As for the question on whether IgA is serious or not, it usually depends on
the patients’ condition. Next I want to introduce two kinds of Hematuresis.
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The first type is acute gross Hematuresis with the signals of acute naked
bloody urine. This case is often seen in children. And gross Hematuresis often
happens after the infections of upper respiratory tract. Naked bloody urine
could continue several hours or several days, some patients also have other
representations such as high blood pressure and the increase in creatinine
levels. Besides that, there are varying degrees of proteinuria or microscopic
bloody urine. And this Hematuresis often relapse after infections in respiratory
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The second type I want to say is the asymptomatic urine abnormalities with
characteristics of occasional or persistent microscopic hematuresis, light
degree of proteinuria. In the physical examinations, we often see the protein in
urine as well as bloody urine, and as for how long the proteinuria or
Hematuresis exists, it is often difficult to predict. And besides, along with
the progression of IgA disease, patients will have a large amount of protein in
urine and severe hypertension and Chronic Renal Failure.
Generally speaking, if there are persistent microscopic Hematuresis together
with proteinuria, or accompanied by hypertension or other symptoms, the
prognosis is not so good. And gross Hematuresis is usually good.
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