2014年12月26日星期五

Do You Know Hormone Is Very Severe

Do You Know Hormone Is Very Severe
Hormone therapy is the most important anti-inflammatory lupus erythematosus, immune-suppressing drugs. Corticosteroids erythematosus than 50 years of history, it is not long in the history of successful experience and lessons of failure, in continuous exploration, there are off to explore the process, people have come up any drug applications there are two aspects of its positive and negative effects on hormones, it can be said with a good life-saving drugs to its analogy to the bridge leading to the road to health is not an exaggeration, but used poorly, but also become hormone poison, its side effects can not be ignored, in general, the majority of its side effects and dosage and treatment duration.

1 Infection: Because it can inhibit the body's response to inflammation, leaving the body's ability to fight infection decreased, therefore, superficial or minor infections may evolve into a systemic infection, quiescent infection could turn into active infection, enabling potential lesions such as purulent lesions, tuberculosis and other activities and proliferation, it usually should pay attention to the prevention of infection, careful observation of the disease, reduction in time and, if necessary, disable, and when there is an acute infection poisoning occurs, must be adequate and effective with the application of antibiotics, tuberculosis merge with a sufficient amount of anti-TB drug use.

2, The Body Changes: Many patients with hormone therapy can change posture, which affects the mental, emotional, because of the long-term use of steroids can make fat redistribution can occur in patients moon face, buffalo hump, trunk fat, skinny limbs concentric obesity and other body change, but also acne, hirsutism, skin purple lines and other effects of beauty.

3. Diabetes: Hormone can increase glycogen, add sugar, induced diabetes, with plenty of corticosteroids should observe the blood, urine changes, hyperglycemia should be given hypoglycemic agents, insulin therapy can be applied when necessary, but with the reduction in the amount of the hormone, hypoglycemic agents or insulin dosage can be reduced.

4. Osteoporosis: Hormone can make bone demineralization, into osteoporosis, osteoporosis refers to bone mass per unit volume reduction, as if building a house to reduce the amount of steel, as is likely to cause fracture. Aseptic bone necrosis, especially occurs in the femoral head osteonecrosis is also a common complication, but its pathogenesis may be the femoral head bone stock and capillary blood circulation disorder caused by inflammation and necrosis, because of necrosis The reason is not a bacterial infection caused, also called aseptic necrosis of the femoral head. Therefore, patients must be long-term use of hormone regular bone densitometry, be aware of while taking hormones, vitamins and calcium preparations add services, so reduce corticosteroid-induced bone reduction, prevention and treatment of osteoporosis osteoporosis, proper physical exercise can promote bone blood circulation, promote metabolism, the prevention of osteoporosis and osteonecrosis have some help. Calcium is a long-term task, be sure to hold the patient in order to balance, perseverance in order to achieve better results.

5, Peptic Ulcer: Hormones can stimulate gastric acid, pepsin secretion of digestive juices too often can cause gastritis, gastric and duodenal ulcers, bleeding or perforation, such as occur in patients with gastrointestinal symptoms when taking hormones with antacids with clothing to protect the gastric mucosa from damage, clinical commonly used ranitidine, Chen Xiang Lu Lu hundred, etc., can be used as the routine use of oral steroid medication synergistic drugs.

6, Electrolyte Imbalance And Hypertension: Hormones can cause sodium retention and cause edema, there are many patients with hypertension, due to potassium excretion, patients often hypokalemia occurs, congestive heart failure or significant peripheral edema patients should selection of a small water and salt metabolism hormones, regularly check the patient's electrolyte balance.

Hormone therapy is often complicated by hypertension, especially in patients with lupus kidney, this time, on the one hand to minimize the amount of hormones, on the one hand the use of appropriate anti-hypertensive drugs, such as nifedipine, captopril and so on. Although some anti-hypertensive drugs may cause side effects of lupus constitution, but after weighing the pros and cons of using still decisive.

7. Other:Patients may appear obvious excitement, irritability when a large number of corticosteroids, euphoria, mental allergies, insomnia, and depression or psychosis can occur, a large number of long-term use of steroids may be muscle weakness, muscle atrophy, and even myositis, increased intraocular pressure, or glaucoma, sebaceous gland dysfunction and so on. Irregular menstruation or amenorrhea is also very common.

I am a physician assistant nephropathy, kidney disease if you have questions regard online consultation can email me or leave a message, my E-mail address: ckdstage@hotmail.com

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