Stem cell therapy is a biotherapy. It brings new hope for people with
refractory and incurable diseases. In clinic, it has showed enormous curative
effects in treating kidney disease.
Stem Cell Therapy has already been used in clinic in some countries to treat
chronic kidney failure fundamentally. Stem cells are a group of cells which have
the capacity of self-update and differentiation. They can produce amount of
daughter cells under proper conditions. We capitalize on the self-update and
differentiation capacity of the stem cells to repair damaged inherent cells and
recover kidney function. After stem cells are transfused to human body, they
will transfer to kidney lesions automatically through the function of automatic
homing, generate kinds of desired cells and then repair the connatural renal
cell, recover renal function and block up and reverse the progression of renal
fibrosis.
Features of stem cell therapy
1. It is widely used to treat diseases and conditions.
2. Free of toxicity and immune rejection.
3. The best carrier of immunization and gene therapy.
4. It can be used before patient understanding pathogenesis completely.
With stem cell therapy,the patients do not need have surgery. So there is no
surgical risk in treating disease.As stem cells are primary cells with weak
antigenicity on the surface, they will not cause rejection reaction after after
being injected into body.
Indications of stem cell therapy
I. Renal injury caused by Autoimmune Diseases and connective tissue disease:
Lupus Nephritis, Anaphylactic Purpura Nephritis, Glomerular Basement Membrane
Disease, Primary Renal Vasculitis, Chronic Infectious Arthritis, Ankylosing
Spondylitis, Psoriasis, Sicca Syndrome, Scleroderma, Polymyositis,
Dermatomyositis, Behcet's Disease Etc.
II. Primary kidney disease such as Primary Nephrotic Syndrome, Acute Glomerulonephritis,Chronic Glomerulonephritis,IgA Nephropathy,MPGN,FSGS,and Membrane Proliferative Glomerulonephritis.
III. Renal injury caused by Metabolic Diseases: Diabetic Nephropathy,
Hyperuricemic Nephropaihy and hypokalemic nephropathy.
IV. Renal tubular disease and renal interstitial disease: Renal Tubular
Acidosis, various kinds of acute and chronic interstitial nephritis;
V. Renal injury caused by infectious diseases: hepatitis B Virus associated
glomerulonephritis, hepatitis C Virus associated glomerulonephritis
VI. cardiac function and IV
VII. Cardiorenal Syndrome and Hepatorenal Syndrome
VIII.Renal Injury caused by hypertension.
IX.Hereditary kidney diseases: Alport nephritis, thin glomerular basement
membrane disease, Fabry disease etc.;
X. Polycystic Kidney Disease
Contraindications of Stem Cell Therapy
I. Patient who is allergic to stem cell or patient with serious allergy;
II. pregnant women (woman in lactation period is allowed)
III. Infected patients who is still out of control;
IV. Serious mental illness patient, including patient with tristimania;
V. Severe Hypertension (BP is higher than 160/100mmHg)
VI. Patient with III and IV cardiac function, coronary disease, unstable
angina, myocardial ischemia
VII. Patients with obvious renal atrophy
VIII. Patients with severe bleeding tendency
IX. Patients who are taking part in clinical research.
X. Polycystic Kidney Disease
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