Alert for Systemic Lupus Erythematosus(SLE) Complications

Answer to this question is yes. Because in systemic lupus erythematosus patients, about half of patients with clinical lupus nephritis, as follows:
1, light nephritis: no related symptoms, with normal renal function, only proteinuria, urinary tube, microscopic hematuria.
2, nephrotic syndrome (disorder): a large number of proteinuria, hypoalbuminemia, high degree of edema, but does not increase blood cholesterol, pathological slow progress.
3, chronic nephritis: patients showed varying degrees of edema, hypertension, proteinuria, and renal dysfunction deformed red blood cells in urine.
4, uremia: This is the outcome of lupus nephritis is a common cause of death in patients. 5, acute nephritis; facial edema, oliguria, transient hypertension, proteinuria, hematuria clear, red blood cell casts in urine, a transient azotemia.
6, distal renal tubular toxicity: At this time concentrated urine kidney function and regulation of acid-base balance dysfunction.

Why lupus nephritis patients prone to it? To answer this question, first of all from the structure and function of the kidneys talk. Renal excretion is one of the most important organs of the body. Left and right kidneys, located in the waist, retroperitoneal, its size, weight, age, sex and different. Kidney from renal units, nearly glomus complexes, as well as renal interstitial blood vessels, nerves and other components. Each kidney is about 1 million nephrons. Each nephron by the glomerulus, the renal capsule, tubular, etc., in fact, each glomerulus is a capillary group. There are about complex human liters of blood through the renal filtration. Glomerular filtration rate with blood, and the absorption of tubular secretion of excretory function, and ultimately the formation of urine excreted.

Systemic lupus erythematosus is due to immune dysfunction, to produce a variety of autoantibodies, and thus the formation of immune complexes caused by systemic vasculitis, leading to tissue damage in inflammatory autoimmune diseases. That being the case, then the group will bear the brunt of the glomerular capillary, the researchers confirmed: antinuclear antibodies in anti-double stranded DNA antibodies, and glomerular DNA combine to form immune complex deposition in the glomerular capillaries, The activation of complement and the release of chemokines attract neutrophils, which neutrophil degranulation time and release of inflammatory mediators leading to glomerulonephritis. Moreover, in addition to the kidney glomeruli other vein, there is also the inflammatory response, which formed a whole nephritis, whether glomerular or tubules are affected, and eventually cause damage to the kidneys function.

Although lupus erythematosus lupus nephritis more serious disease, but if aggressive treatment, there is still hope of cure, in treatment, Western medicine is a hormone used to add other small dose immunosuppressive drug combination, can receive good results . Especially since traditional Chinese medicine involved in the treatment of this disease, through diagnosis and treatment, not only to treat the disease itself, but also against or reduce the side effects of western medicine, so lupus treatment appeared more optimistic outlook.

I am in Shijiazhuang Kidney Disease Hospital in a doctor, our hospital combined therapy integrated traditional Chinese and western medicine the essence of traditional Chinese medicine and western medicine in the treatment of kidney disease, a new and effective innovation for kidney disease treatment, if you have kidney disease need to answer, can you give us online doctor, also can also email me, my E-mail address is: ckdstage@hotmail.com.