Is it safe to give paracetamol when IgA nephropathy patient

Some IgA nephropathy patients will use paracetamol when they have pain, but is it safe? Experts from Shijiazhuang kidney disease hospital help you solve this problem.Improve Kidney Function for IgA Nephropathy in End Stage Renal Disease
IgA Nephropathy patients frequently suffer from headaches apparently connected to their disease (and not necessarily related to high blood pressure). The following headache treatments are offered as safe alternatives to aspirin and non-aspirin pain relievers such as acetaminophen (Tylenol, Excedrin, etc.) and ibuprofen (Motrin, etc.). Aspirin is considered risky in treating children and teens who may have a viral illness, while acetaminophen and ibuprofen are toxic to the kidneys.How to Slow Down the Progression for IgA Nephroapthy Patients with 48% Kidney Function
It is unclear how phenacetin induces injury to the kidney. Bach and Hardy have proposed that phenacetin's metabolites lead to lipid peroxidation that damages cells of the kidney.
Paracetamol is the major metabolite of phenacetin and may contribute to kidney injury through a specific mechanism. In cells of the kidney, cyclooxygenases catalyse the conversion of paracetamol into N-acetyl-p-benzoquinoneimine (NAPQI). NAPQI depletes glutathione via non-enzymatic conjugation to glutathione, a naturally occurring antioxidant. With depletion of glutathione, cells of the kidney become particularly sensitive to oxidative damage.
It isn’t safe to give paracetamol when IgA nephropathy patient has pain?

In Shijiazhuang kidney disease hospital, the most effective treatment for IgA nephropathy is Stem cell Therapy, which combines the good effects of Stem cell Therapy and Micro-Chinese Medicine Osmotherapy. you have a chance to get rid of the pain caused by IgA nephropathy. The curate is as high as 80%.