What Should I Do with Creatinine 4.9 in Stage 3 Kidney Disease

Creatinine is the waste product of our muscle metabolism and the meat we eat. In normal condition, healthy kidneys can filter out the waste products and toxins in blood and keep creatinine level in a normal range. When kidneys are damaged, high creatinine level will occur.
Under normal cases, the creatinine level is 0.6~1.2 mg/dl for male and 0.5-1.1mg/dl for female. As for creatinine level 4.9, it is in stage 3. And if not controlled well, it may develop into kidney failure eventually. Then what is the effective treatment to lower creatinine level 4.9?
Chronic kidney disease can be divided into five stages according to GFR levels. If we match it with creatinine levels, it is stage 1 CKD: <1.6mg/dL; stage 2 CKD: 1.6-2.0mg/dL; stage 3 CKD: 2.1-5.0mg/dL; stage 4 CKD: 5.1-7.9mg/dL; stage 5 CKD: >8.0mg/dL. From here, we can know that creatinine 4.9 means the condition has already developed stage 3 chronic kidney disease which means the moderate loss of kidney function. Also stage 3 chronic kidney disease is such a stage which needs the prompt treatment, otherwise the condition can develop stage 4 chronic kidney disease which requires dialysis or kidney transplant in the near future. Perhaps patients with creatinine 4.9 would like to know How to Stop the Progression of Stage 3 Chronic Kidney Disease.
Blood purification therapy to treat kidney disease, which are hematodialysis, hemofiltration, hemodiafiltration, hemoperfusion, plasmapheresis, immunoadsorption. Each step has its unique function.
Hematodialysis aims at removing micromolecule urotoxins, such as creatinine, blood urea nitrogen, water, electrolyte and so on. So, it is proper to treat stage 3 kidney disease with creatinine 4.9. And the early treatment, the better effect.
Hemofiltration can remove middle molecular substances, such as chemical substances, bilirubin, vitamins, etc.
Hemodiafiltration conbinates the hematodialysis and hemofiltration, which can remove the mediun and small molecular subtances, such as cytokines inflammatory mediators.
Hemoperfusion can remove toxins in medicines and posions.
Plasmapheresis is suitable for autoimmune disease, such as IgA nephropathy, FSGS, Metabolic nephropathy, and transplant rejection.

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