What circumstances would trigger diabetes in children

Children with diabetes is due to inadequate secretion of insulin caused by endocrine and metabolic diseases, carbohydrate, protein and fat metabolism disorder mainly caused by fasting and postprandial hyperglycemia and urine. Clinical manifestations of polydipsia, polyuria, meals and weight loss. Children prone to ketoacidosis, late vascular lesions often cause eye and kidney involvement. Childhood diabetes seen in all ages, and puberty is more common in school age range, no gender differences.

Diabetes is an autoimmune disease, congenital genetic background, the role acquired by a variety of factors make it sick.

1 autoimmune response

It has been demonstrated both humoral and cellular immunity and diabetes. Onset of insulin-dependent diabetes, the body two-thirds of children with beta islet cell antibodies. Some children also measured insulin receptor autoantibodies and islet β cell antibodies.

2 environmental factors

(A) Coxsackie B virus infection, EB virus, mumps virus.

(2) early milk protein, excessive intake of dairy cattle, wherein the casein protein as an antigen, to trigger diabetes. Milk bovine insulin can cause damage to the immune response of human β-cell function.

(3) pharmaceutical and chemical factors.

3 genetic susceptibility

Hereditary, confirmed WBC No. 6 located on the short arm of chromosome histocompatibility complex genes for susceptibility genes.

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