Recurrence of IgAN. A common question about kidney transplants among IgAN
patients is whether the IgAN will come back in the transplanted kidney. The
answer is yes. Current information suggests that if all post-transplant IgAN
patients were biopsied, IgAN would be found to have recurred in up to 50% of
transplants within the first 10 years (and possibly 100% of them by 10-20 years,
but that it leads to loss of the transplanted kidney in about 5 to 10% of
patients (before graft loss occurs for other reasons). It is also thought that
the rate of progression of any recurrence is unlikely to be faster than the
original disease was. Based on that, transplant centers have no hesitation in
transplanting IgAN patients. It's just not considered to be a factor. A kidney
transplant is considered the best overall treatment for renal failure in IgAN
patients after they reach end-stage renal disease. But there is really no way to
predict how fast recurrence might happen in any given individual.
High recurrence rate of IgA Nephropathy after kidney transplant
IgA Nephropathy recurs commonly after a kidney transplant. If
post-transplanted patient with IgAN did a kidney biopsy, approximately 60% of
them would have evidence of the disorder in the biopsy specimen. About 20-40% of
patients actually have abnormal protein or blood detected in the urine due to
recurrent IgA Nephropathy. On average, the recurrent often happens around 2.5
years after the kidney transplant.
It's a treatment. Transplant nephrologists would usually advise you not to
worry about this. In all cases, a kidney transplant is a treatment, not a cure,
no matter what kidney disease caused the renal failure. While every effort will
be made to extend the transplant's life for as long as possible, a kidney
transplant is never promised to last forever, and loss of the kidney due to
rejection is a far greater concern than recurrence of IgAN. In a way, when you
get to that stage, having gotten there due to IgAN is somewhat of a blessing, as
opposed to, say, diabetes. IgAN patients are generally recognized as being among
the very healthiest of kidney patients, other than having kidney failure.
Therefore, the chances of qualifying for a kidney transplant are greater, and
the chances of living a healthy life after the transplant are probably greater
as well. Observations suggest that survival of a cadaveric kidney transplant in
IgAN patients is among the highest among all ESRD patients from various causes,
despite the risk of IgAN recurrence.
In order to treat IgA Nephropathy and Chronic Kidney Disease,we treat our
blood in the first place.Toxins and wastes do damage to blood vessel thus
destroying blood-forming system and coagulation system.Blood Pollution Therapy
is also on the basis of Chinese Medicines.Chinese Medicines provide nutritions
and useful substances for the recovery of blood systems.As the blood system is
regulated,kidney also has a better environment for its recovery.
With the help of Blood Purification,we ensure clear away stasis completely
thus helping our kidneys to realize self-recovery.
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