2014年1月17日星期五

IgA Nephropathy and Kidney Transplants

Recurrence of IgAN. A common question about kidney transplants among IgAN patients is whether the IgAN will come back in the transplanted kidney. The answer is yes. Current information suggests that if all post-transplant IgAN patients were biopsied, IgAN would be found to have recurred in up to 50% of transplants within the first 10 years (and possibly 100% of them by 10-20 years, but that it leads to loss of the transplanted kidney in about 5 to 10% of patients (before graft loss occurs for other reasons). It is also thought that the rate of progression of any recurrence is unlikely to be faster than the original disease was. Based on that, transplant centers have no hesitation in transplanting IgAN patients. It's just not considered to be a factor. A kidney transplant is considered the best overall treatment for renal failure in IgAN patients after they reach end-stage renal disease. But there is really no way to predict how fast recurrence might happen in any given individual.
High recurrence rate of IgA Nephropathy after kidney transplant
IgA Nephropathy recurs commonly after a kidney transplant. If post-transplanted patient with IgAN did a kidney biopsy, approximately 60% of them would have evidence of the disorder in the biopsy specimen. About 20-40% of patients actually have abnormal protein or blood detected in the urine due to recurrent IgA Nephropathy. On average, the recurrent often happens around 2.5 years after the kidney transplant.
It's a treatment. Transplant nephrologists would usually advise you not to worry about this. In all cases, a kidney transplant is a treatment, not a cure, no matter what kidney disease caused the renal failure. While every effort will be made to extend the transplant's life for as long as possible, a kidney transplant is never promised to last forever, and loss of the kidney due to rejection is a far greater concern than recurrence of IgAN. In a way, when you get to that stage, having gotten there due to IgAN is somewhat of a blessing, as opposed to, say, diabetes. IgAN patients are generally recognized as being among the very healthiest of kidney patients, other than having kidney failure. Therefore, the chances of qualifying for a kidney transplant are greater, and the chances of living a healthy life after the transplant are probably greater as well. Observations suggest that survival of a cadaveric kidney transplant in IgAN patients is among the highest among all ESRD patients from various causes, despite the risk of IgAN recurrence.
In order to treat IgA Nephropathy and Chronic Kidney Disease,we treat our blood in the first place.Toxins and wastes do damage to blood vessel thus destroying blood-forming system and coagulation system.Blood Pollution Therapy is also on the basis of Chinese Medicines.Chinese Medicines provide nutritions and useful substances for the recovery of blood systems.As the blood system is regulated,kidney also has a better environment for its recovery.

With the help of Blood Purification,we ensure clear away stasis completely thus helping our kidneys to realize self-recovery.

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