2014年9月5日星期五

Do you know why the treatment of PKD must first control blood pressure

Do you know why the treatment of PKD must first control blood pressure
Polycystic kidney disease is a hereditary disease, polycystic kidney disease patients if not treated in time or due to improper treatment can cause the occurrence of uremia. The primary method of treatment in the clinical uremia is timely to control blood pressure.

ADPKD addition to involving the kidneys, but also affect multiple organs and tissues. About one-third of patients have liver cysts, the number of cysts increased with age, clinical manifestations of liver pain, discomfort and early sense of fullness and so on. Cysts can also occur in the pancreas, spleen, esophagus, thyroid, endometrial, seminal vesicles, and epididymis, these isolated cysts do not cause clinical symptoms. Heart valve abnormalities, cardiac hypertrophy and congenital heart disease, is another common ADPKD kidney manifestations. 83% of patients with end-stage ADPKD confirmed by barium enema colon diverticulum. Aneurysms can occur in the brain arteries, abdominal aorta, thoracic aorta, atrial septal and coronary etc., cystic or spindle.

Polycystic kidney disease blood pressure control is very important

Hypertension is one of the common clinical manifestations of polycystic kidney disease, polycystic kidney disease is the earliest clinical manifestations. Foreign reports increase in blood pressure in patients with polycystic kidney disease than the general population as early as ten years, 60% of patients with renal abnormalities occur before there is increased blood pressure. If you enter ESRD stage, almost all patients with hypertension. Polycystic kidney disease is similar to other types of kidney disease, high blood pressure is an important factor affecting the progress of renal function, and it is a major risk factor for cardiovascular complications.

In recent years, in the treatment of polycystic kidney disease, a series of clinical studies, but the most viable clinical interventions or for blood pressure control in patients with polycystic kidney disease. Although early and effective antihypertensive therapy is thought to be slow disease progression, an important measure to reduce cardiovascular complications, but the application in the treatment of polycystic kidney disease in patients with hypertension gluttonous matter what the buck has not completely unified.

Some scholars have confirmed that in patients with polycystic kidney disease in, RAAS system is in continuous active, and can be observed early in the disease's high glomerular filtration phenomenon, indicating activation of the RAAS in hypertensive patients with polycystic kidney disease plays an important role in the occurrence, so RAAS system in patients with hypertension, polycystic kidney disease may be the best therapeutic targets. Meanwhile, some scholars study found that in patients with polycystic kidney disease in the sympathetic nervous system is also activated.

In short, strict control of blood pressure is essential for the protection of the heart and kidney function in patients with polycystic kidney disease. Early antihypertensive treatment should be carried out, the vast majority get good treatment effect.

Therefore, in the event of polycystic kidney disease when blood pressure should be controlled in a timely manner, after which the patient's condition and the roots of the regular symptoms due to symptomatic treatment. Avoid improper treatment caused some serious consequences.

If you have kidney disease troubled, you can give us Shijiazhuang Kidney Disease Hospital doctors message or communicate with our online doctor, our doctors will respond promptly to your question.

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